Adrian Hernandez MD, MHS

Adrian Hernandez

Core Faculty

Adrian Hernandez, MD, MHS


MD, University of Texas at Dallas

Dr. Hernandez is a cardiologist with extensive experience in clinical research ranging from clinical trials to outcomes and health services research. He is Vice Dean for Clinical Research in the School of Medicine and a Faculty Associate Director of the DCRI. He leads research programs focused on understanding population health, generating real-world evidence, and improving patient-centered outcomes through development of new therapies and better care delivery in our national health system. He is the Coordinating Center Principal Investigator for multiple networks and clinical trials such as the NHLBI’s Heart Failure Clinical Research Network, PCORI’s National Patient-Centered Clinical Research Network (PCORnet) and NIH’s Health System Collaboratory. A central aim of these networks is to transform clinical research by uniting patients, clinicians, health systems, and electronic health data to improve population health and decision making. Dr. Hernandez has over 450 published articles in top peer-reviewed journals including the New England Journal of MedicineJournal of the American Medical Association, and Lancet.

Newman JD, Bhatt DL, Rajagopalan S, Balmes JR, Brauer M, Breysse PN, et al. Cardiopulmonary Impact of Particulate Air Pollution in High-Risk Populations: JACC State-of-the-Art Review. J Am Coll Cardiol. 2020 Dec 15;76(24):2878–94.

Yang S, Li F, Starks MA, Hernandez AF, Mentz RJ, Choudhury KR. Sample size requirements for detecting treatment effect heterogeneity in cluster randomized trials. Stat Med. 2020 Dec 10;39(28):4218–37.

Fudim M, Ashur N, Jones AD, Ambrosy AP, Bart BA, Butler J, et al. Implications of peripheral oedema in heart failure with preserved ejection fraction: a heart failure network analysis. Esc Heart Fail. 2020 Dec 9;