Adrian Hernandez MD, MHS

Adrian Hernandez

Core Faculty

Adrian Hernandez, MD, MHS

Degree

MD, University of Texas at Dallas

Dr. Hernandez is a cardiologist with extensive experience in clinical research ranging from clinical trials to outcomes and health services research. He is Vice Dean for Clinical Research in the School of Medicine and a Faculty Associate Director of the DCRI. He leads research programs focused on understanding population health, generating real-world evidence, and improving patient-centered outcomes through development of new therapies and better care delivery in our national health system. He is the Coordinating Center Principal Investigator for multiple networks and clinical trials such as the NHLBI’s Heart Failure Clinical Research Network, PCORI’s National Patient-Centered Clinical Research Network (PCORnet) and NIH’s Health System Collaboratory. A central aim of these networks is to transform clinical research by uniting patients, clinicians, health systems, and electronic health data to improve population health and decision making. Dr. Hernandez has over 450 published articles in top peer-reviewed journals including the New England Journal of MedicineJournal of the American Medical Association, and Lancet.

Shoji S, Cyr DD, Hernandez AF, Velazquez EJ, Ward JH, Williamson KM, et al. Win Ratio Analyses Using a Modified Hierarchical Composite Outcome: Insights From PARAGLIDE-HF. Am Heart J. 2025 Feb;280:70–8.

Duran JM, Shrader P, Hong C, Haddad F, Santana EJ, Cauwenberghs N, et al. Abnormal Exercise Electrocardiography With Normal Stress Echocardiography Is Associated With Subclinical Coronary Atherosclerosis. Circ Cardiovasc Imaging. 2025 Jan 13;e017380.

Shah NP, Mulder H, Lydon E, Chiswell K, Hu X, Lampron Z, et al. Real-world exploration of LDL-cholesterol management in patients with atherosclerotic cardiovascular disease. Am Heart J. 2025 Jan;279:50–8.