Adrian Hernandez MD, MHS

Adrian Hernandez

Core Faculty

Adrian Hernandez, MD, MHS


MD, University of Texas at Dallas

Dr. Hernandez is a cardiologist with extensive experience in clinical research ranging from clinical trials to outcomes and health services research. He is Vice Dean for Clinical Research in the School of Medicine and a Faculty Associate Director of the DCRI. He leads research programs focused on understanding population health, generating real-world evidence, and improving patient-centered outcomes through development of new therapies and better care delivery in our national health system. He is the Coordinating Center Principal Investigator for multiple networks and clinical trials such as the NHLBI’s Heart Failure Clinical Research Network, PCORI’s National Patient-Centered Clinical Research Network (PCORnet) and NIH’s Health System Collaboratory. A central aim of these networks is to transform clinical research by uniting patients, clinicians, health systems, and electronic health data to improve population health and decision making. Dr. Hernandez has over 450 published articles in top peer-reviewed journals including the New England Journal of MedicineJournal of the American Medical Association, and Lancet.

Mann DL, Hernandez AF, Braunwald E. Could Neprilysin Be Already Inhibited by BNP in the LIFE Trial?-Reply. Jama Cardiol. 2022 Jun 1;7(6):657–8.

Jones WS, Wruck LM, Harrington RA, Hernandez AF. Iterative approaches to the use of electronic health records data for large pragmatic studies. Contemp Clin Trials. 2022 Jun;117:106789.

Harrington J, Jones WS, Udell JA, Hannan K, Bhatt DL, Anker SD, et al. Acute Decompensated Heart Failure in the Setting of Acute Coronary Syndrome. Jacc Heart Fail. 2022 Jun;10(6):404–14.