Research Team
Matt D'Ambrosio
Contact
Focus Areas
Degree
Bachelor of Science, Environment and Sustainability, Cornell University
Matt D'Ambrosio is a policy analyst with the Duke-Margolis Institute for Health Policy. His work with the Real-World Evidence Collaborative focuses on how modern data sources, such as electronic health records and registries, can support more informed health care decision-making. Matt manages stakeholder engagement with medical product sponsors, health systems, academia, and the public sector as part of his activities with both with the RWE Collaborative and the Institute's U.S. FDA cooperative agreements. Additionally, Matt collaborates with partners across Duke University on policy research at the intersection of climate change, sustainability, and health care. He is particularly interested in how incentives for more efficient, high-value care align with addressing community-level health challenges driven by ecological change. Prior to joining Duke-Margolis, Matt worked for Charlie Health and Stony Brook University. He received his B.S. from Cornell University, where he was Executive-Editor of the Cornell Lunatic. Matt is based in Washington, DC and lives in Arlington, VA.
White Paper
Data Curation Best Practices and Innovations for Real-World Evidence Generated Using Electronic Health Record-Sourced Data
Matt D'Ambrosio, Patrick Rodriguez, Nora Emmott, Rachele Hendricks-Sturrup
2026
Read MoreWhite Paper
Operational Tools and Best Practices to Support Electronic Health Record-Sourced Data Quality, Relevance, and Reliability at the Data Accrual Phase
Matt D'Ambrosio, Patrick Rodriguez, Nora Emmott, Rachele Hendricks-Sturrup
2025
Read MoreWhite Paper
Lessons from Learning Health Care Systems and Recommendations for Successful Implementation
Trevan Locke, Sandra Yankah, Matt D’Ambrosio, Rachele Hendricks-Sturrup
2023
Read MoreWhite Paper
Harnessing the Potential of Real-World Evidence Master Protocols
Adam Aten, Matthew D’Ambrosio, Rachele Hendricks-Sturrup
2023
Read MoreIssue Brief
FDA User Fee Reauthorization and the Value of Real-World Evidence
Adam Aten, Nora Emmott, Matthew D’Ambrosio, Rachele Hendricks-Sturrup
2022
Read MoreIssue Brief
COVID-19 Test to Treat Pathways: Policy Options for Achieving National Implementation
Brian Canter, Matt D’Ambrosio, Katie Greene, Morgan Romine, Mark McClellan
2022
Read MorePolicy Brief
Maximizing the Benefit of COVID-19 Therapeutics: Considerations for State Public Health Officials
The Duke-Margolis Center for Health Policy and the Association of State and Territorial Health Officials
2022
Read MorePolicy Brief
Preparing for the Authorization of COVID-19 Antivirals
Brian Canter, Matt D’Ambrosio, Katie Greene, Morgan Romine, Mark McClellan
2021
Read MorePolicy Brief
Equitable State Allocation: Promising Practices for Promoting Utilization of COVID-19 Monoclonal Antibody Treatments
Brian Canter, Matt D’Ambrosio, Katie Greene, Andrea Thoumi, Morgan Romine, Mark McClellan
2021
Read More