Nimmi Ramanujam PhD

Nimmi Ramanujam

Core Faculty

Nimmi Ramanujam, PhD

Focus Areas
Degrees

PhD, University of Texas at Austin

MS, University of Texas at Austin

Dr. Ramanujam is an innovator, educator and entrepreneur. Her mission is to develop technology that will have wide reaching impact in women’s health. She directs the center for Global Women’s Health Technologies at Duke where she empowers trainees at Duke and beyond to create impactful solutions to improve the lives of women and girls globally. 

Dr. Ramanujam has spent the last two decades developing precision diagnostics and most recently precision therapeutics for breast and cervical cancer, with a focus on addressing health disparities. She has more than 20 patents to-date and over 150 publications for screening, diagnostic, and surgical applications. She has raised over $30M of funding to pursue these innovations through a variety of funding mechanisms including NIH R01s and R21s, NIH Bioengineering Partnerships, NCI Academic Industry Partnerships, NIH Small Business grants and USAID funding. As the founding director of the Center for Global Women’s Health Technologies at Duke, she has developed a consortium of over 50+ partners including international academic institutions and hospitals, non-governmental organizations, ministries of health, and commercial partners; this consortium is working to ensure that the technologies developed at the center are adopted by cancer control programs in geographically and economically diverse healthcare settings. 

Ramanujam’s research on women’s cancers has centered on translational and laboratory research of relevance to breast and cervical cancer. While her guiding principles are similar across breast and cervical cancer, the technical challenges needed to tackle these cancers are inherently different. In the case of cervical cancer prevention, her focus is to develop strategies that reduce attrition to treatment including early screening and diagnostics. In the breast cancer care cascade, clinical care has principally pivoted towards a focus on how to inform the effectiveness of cancer therapy whether it is surgery or systemic therapy and that is where she has focused her efforts via molecular and metabolic imaging.  A third area in her research program focuses on low cost ablative strategies for local control of cancer in resource limited settings. She has also created two companies Zenalux and Calla Health to commercialize her breast and cervical imaging products, respectively. Additionally, she has created three social innovations programs: WISH to impact cervical cancer prevention in low resource settings, IGNITE to scale social innovation education to students globally and the Calla Campaign to bridge inequities in sexual and reproductive health inequities through story-telling and art.

Nimmi has received recognition for her work through the TR100 Young Innovator Award from MIT, the Global Indus Technovator award from MIT, Era of Hope Scholar awards from the DOD, the Stasnell Family award from the Pratt School of Engineering at Duke, the Emerging Leader in Global Health Award from the Consortium of Universities in Global Health, the Social Impact Abie Award from AnitaB.org, the Biophotonics Technology Innovator Award from the International Society for Optics and Photonics, and the Women in Molecular Imaging Leadership Award (WIMIN) from the World Molecular Imaging Congress (WMIC). She is a fellow of several optical and biomedical engineering societies including OSA, SPIE and AIMBE. She has also been elected to the National Academy of Inventors and is a Fullbright Fellow. She is co-editor of the Handbook of Biomedical Optics. She has presented the global impact of her work at the United Nations. She has been a TedX speaker.

Morhard R, Mueller JL, Tang Q, Nief C, Chelales E, Lam CT, et al. Understanding Factors Governing Distribution Volume of Ethyl Cellulose-Ethanol to Optimize Ablative Therapy in the Liver. Ieee Transactions on Bio Medical Engineering. 2020 Aug;67(8):2337–48.

Asiedu MN, Skerrett E, Sapiro G, Ramanujam N. Combining multiple contrasts for improving machine learning-based classification of cervical cancers with a low-cost point-of-care Pocket colposcope. In: Proceedings of the Annual International Conference of the Ieee Engineering in Medicine and Biology Society, Embs. 2020. p. 1148–51.

Bowden AK, Durr NJ, Erickson D, Ozcan A, Ramanujam N, Jacques PV. Optical Technologies for Improving Healthcare in Low-Resource Settings: introduction to the feature issue. Biomedical Optics Express. 2020 Jun;11(6):3091–4.