Project Report
Advancing Clinical Trials at the Point of Care (ACT@POC)
Advancing Clinical Trials at the Point of Care (ACT@POC)
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New from ACT@POC
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About ACT@POC
Additional Coalition Materials
Advancing Clinical Trials at the Point of Care Coalition: FAQs
Open Letter From Health Systems and Their Partners Committed to Better Evidence
Coalition Overview
Statements from Coalition Members
Coalition Members
Ascension
Ascension is committed to delivering compassionate, personalized care to all, with special attention to persons living in poverty and those most vulnerable.
The Broad Institute
The Broad Institute of MIT and Harvard is a research organization that convenes a community of researchers from across many disciplines and partner institutions—MIT, Harvard, and Harvard-affiliated hospitals.
Based in Cambridge, Massachusetts, the Broad Institute was founded in 2004 to fulfill the promise of genomic medicine—three years after completion of the Human Genome Project, which Broad scientists helped create and lead. Our origins are rooted in genomics, and as biomedical research and knowledge have expanded since 2004, so have we. Our researchers are deeply collaborative, nimbly launching innovative, high-risk projects at every scale, inventing new technologies, building and implementing computational tools, developing new therapeutics to advance into the clinic, mentoring and training the next generation of scientists, and sharing our data and tools openly to enable breakthroughs anywhere.
Clinical Trials Transformation Initiative (CTTI)
At its most fundamental level, the Clinical Trials Transformation Initiative (CTTI) is a group of individuals and organizations that want to improve the quality and efficiency of clinical trials. It was co-founded by Duke University and the U.S. Food and Drug Administration in 2007 in an effort to identify and address challenges to well-designed, properly executed clinical trials, and offer recommendations to improve and modernize research.
Critical Path Institute
Critical Path Institute (C-Path) is an independent, nonprofit organization established in 2005 as a public and private partnership. C-Path’s mission is to catalyze the development of new approaches that advance medical innovation and regulatory science, accelerating the path to a healthier world. An international leader in forming collaborations, C-Path has established numerous global consortia that currently include more than 1,600 scientists from government and regulatory agencies, academia, patient organizations, disease foundations, and dozens of pharmaceutical and biotech companies. C-Path US is headquartered in Tucson, Arizona and C-Path, Ltd. EU is headquartered in Dublin, Ireland, with additional staff in multiple other locations. For more information, visit c-path.org and c-path.eu.
Duke Clinical Research Institute
The Duke Clinical Research Institute, part of the Duke University School of Medicine, is the world’s largest academic clinical research organization. We conduct innovative research to deliver on our mission to share knowledge that improves health around the world. DCRI projects are led by physician scientists whose grounding in patient care helps to inform their research, and supported by staff who have deep expertise in operationalizing global studies. Learn more at dcri.org.
Duke Health
Duke Health is committed to conducting innovative basic and clinical research, rapidly translating breakthrough discoveries to patient care and population health, providing a unique educational experience to future clinical and scientific leaders, improving the health of populations, and actively seeking policy and intervention-based solutions to complex global health challenges. Underlying these ambitions is a belief that Duke Health is a destination for outstanding people and a dedication to continually explore new ways to help our people grow, collaborate and succeed. Learn more at Duke Health.
Duke-Margolis Institute for Health Policy
The mission of the Duke-Margolis Institute for Health Policy at Duke University is to improve health, health equity, and the value of health care through practical, innovative, and evidence-based policy solutions. For more information, visit healthpolicy.duke.edu.
Morningside Center for Innovative and Affordable Medicine
The Morningside Center for Innovative and Affordable Medicine (Morningside Center) is an interdisciplinary unit within the Woodruff Health Sciences Center at Emory University. Extending the vision of GlobalCures Inc., a non-profit medical research organization, the Morningside Center was established at Emory in 2019 through a gift from the Morningside Foundation to promote research, education, and advocacy for effective and affordable medical treatments.
Intermountain Healthcare
Located in Utah, Idaho, and Nevada, Intermountain Healthcare is a nonprofit system of 25 hospitals, 225 clinics, the Intermountain Medical Group with some 2,700 employed physicians and advanced care practitioners, a health plans division called SelectHealth, Homecare, and other health services. Helping people live the healthiest lives possible, Intermountain is committed to improving community health and is widely recognized as a leader in transforming healthcare by using evidence-based best practices to consistently deliver high-quality outcomes and sustainable costs.
Mayo Clinic
Mayo Clinic is a nonprofit organization committed to innovation in clinical practice, education and research, and providing compassion, expertise and answers to everyone who needs healing. Visit the Mayo Clinic News Network for additional Mayo Clinic news. For information on COVID-19, including Mayo Clinic's Coronavirus Map tracking tool, which has 14-day forecasting on COVID-19 trends, visit the Mayo Clinic COVID-19 Resource Center.
Medable
Medable is on a mission to get effective therapies to patients faster by transforming clinical drug development with disruptive technologies. The company’s digital platform streamlines design, recruitment, retention and data quality for decentralized trials, replacing siloed systems with integrated digital tools, data and interfaces to accelerate trial execution. Medable connects patients, sites and clinical trial teams to improve patient access, experience and outcomes. Medable’s software has been named a Leader in the industry by both Everest Group and IDC. Medable is a privately held, venture-backed company headquartered in Palo Alto, California.
MITRE
MITRE’s mission-driven teams are dedicated to solving problems for a safer world. Through our public-private partnerships and federally funded R&D centers, we work across government and in partnership with industry to tackle challenges to the safety, stability, and well-being of our nation.
Quantum Leap Healthcare Collaborative
Quantum Leap Healthcare Collaborative is a 501C(3) charitable organization established in 2005 as a collaboration between medical researchers at University of California, San Francisco and Silicon Valley entrepreneurs. Our mission is to integrate high-impact research with clinical processes and systems technology, resulting in improved data management and information systems, greater access to clinical trial matching and sponsorship, and greater benefit to providers, patients and researchers. Our goal is to improve and save lives. Quantum Leap provides operational, financial, and regulatory oversight to the I-SPY Trials. For more information, visit www.QuantumLeapHealth.org.
University of Massachusetts Department of Medicine
The Department of Medicine’s vision is to be the national leader in the delivery of innovative and high-quality patient care, education programs and in transformative basic and clinical research.
UCI Health Affairs
Founded in 2017 with a $200 million gift from Orange County philanthropists Susan and Henry Samueli, UCI Health Affairs is a first of its kind health sciences enterprise and is unique to Orange County, Calif. Together, the Susan & Henry Samueli College of Health Sciences and UCI Health form UCI Health Affairs, led by Vice Chancellor Steve Goldstein, MA, MD, PhD, FAAP. Susan & Henry Samueli College of Health Sciences is translating our tripartite mission to “discover, teach, heal,” into the diverse healthcare workforce of the future and groundbreaking scientific discoveries. Creating a first-of-its-kind alliance across health disciplines, the college comprises the School of Medicine, the Sue & Bill Gross School of Nursing, the recently launched School of Pharmacy & Pharmaceutical Sciences, the future School of Population & Public Health (scheduled to be accredited in 2021), the Susan Samueli Integrative Health Institute, and research units focused on cancer, clinical translational science, precision health and stem cells. The college shares a robust synergy with UCI Health, the only academic health system in Orange County. UCI Health Affairs is transforming education, discovery, and patient care to benefit the region, state and nation.
Vanderbilt University Medical Center
Managing more than 2 million patient visits each year, Vanderbilt University Medical Center (VUMC) is one of the largest academic medical centers in the Southeast, and is the primary resource for specialty and primary care in hundreds of adult and pediatric specialties for patients throughout Tennessee and the Mid-South. The School of Medicine’s biomedical research program is among the nation’s top 10 in terms of National Institutes of Health peer review funding, receiving more than $500 million in public and private awards during 2016. The Medical Center is the region’s locus of postgraduate medical education, with over 1,000 residents and fellows training in more than 100 specialty areas. Vanderbilt University Adult Hospital and the Monroe Carell Jr. Children’s Hospital at Vanderbilt are recognized each year by U.S. News & World Report’s Best Hospitals rankings as national leaders, with 19 nationally ranked adult and pediatric specialties. Through the Vanderbilt Health Affiliated Network, VUMC is working with over 60 hospitals and 5,000 clinicians across Tennessee and five neighboring states to share best practices and bring value-driven and cost-effective health care to the Mid-South.
Our Mission
Through the exceptional capabilities and caring spirit of its people, Vanderbilt will lead in improving the healthcare of individuals and communities regionally, nationally and internationally. We will combine our transformative learning programs and compelling discoveries to provide distinctive personalized care.