Clinical Trial Modernization

Clinical Trial Modernization

The clinical research enterprise has evolved greatly over the past several decades, with a clear need for evidence-based policy research and solutions to better marry clinical care and research. Duke-Margolis has demonstrated policy leadership with portfolio focused on clinical trial modernization, which seeks to improve efficacy and efficiency of clinical trials with a broad goal of improving practical evidence generation and application. Innovating our approach to clinical trials is vital to translate research into clinical practice and in turn improve outcomes at the individual and public health level. New approaches to clinical trials have the potential to address longstanding access barriers that continue to limit representative access to trials for hardly reached populations. Moreover, during public health emergencies, having “warm-base” trial capacity in place to quickly respond and establish trials is imperative. Harnessing technology and policy innovation to target these challenges is a bold goal which requires collaboration across sectors. Duke-Margolis collaborates with many players in this space, including government, academic, industry, and health system partners, to achieve this vision together.

Current Projects

Duke Margolis Team

Brian Canter Headshot

Brian Canter, Ph.D.

Policy Research Associate

Cameron Joyce Headshot

Cameron Joyce, MPA

Senior Policy Analyst

Trevan Locke headshot

Trevan Locke, PhD

Assistant Research Director


Marianne Hamilton Lopez, PhD, MPA

Senior Research Director, Biomedical Innovation
Faculty Director of the Duke-Margolis Postdoctoral Associates & Affiliated Fellows Program
Adjunct Associate Professor
Senior Team Member
Margolis Core Faculty

Valerie Parker Headshot

Valerie Parker, MS

Policy Research Associate


Sandra E. Yankah, Ph.D.

Postdoctoral Researcher